HitPredict

Interactor 1: F262 (O60825)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	12853467, 33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 245
+	Hs
		241684 F262_HUMAN (1-505): 0: 758: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		241685 F262_HUMAN (1-505): 0: 758: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		241679 F262_HUMAN (1-505): 0: 758: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		241688 F262_HUMAN (1-505): 0: 758: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		241683 F262_HUMAN (1-505): 0: 758: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		646933 F263_HUMAN (6-480): 0: 659: 70.44		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927095 F263_HUMAN (6-480): 0: 659: 70.44		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683382 F263_HUMAN (6-480): 0: 659: 70.44		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		909615 F264_HUMAN (6-451): 0: 623: 69.51		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		646934 F264_HUMAN (6-451): 0: 623: 69.51		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927096 F264_HUMAN (6-451): 0: 623: 69.51		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683383 F264_HUMAN (6-451): 0: 623: 69.51		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		982053 F263_HUMAN (6-480): 0: 659: 70.44		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904618 F263_HUMAN (6-480): 0: 659: 70.44		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		982054 F264_HUMAN (6-451): 0: 623: 69.51		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904619 F264_HUMAN (6-451): 0: 623: 69.51		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		578306 PGAM1_HUMAN (247-450): 1.16e-72: 232: 20.08		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59