HitPredict

Interactor 1: PRAF2 (O60831)
PRA1 family protein 2
Gene: PRAF2

Interactor 2: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 189
+	Hs
		277693 PRAF3_HUMAN (3-176): 1.13e-76: 228: 45.40		REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00
+	Hs
		961877 PRAF1_HUMAN (5-140): 2.38e-37: 128: 22.79		REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00
+	Mm
		1247007 PRAF3_MOUSE (3-175): 1.06e-75: 226: 45.09		REEP3_MOUSE (54-176): 4.15e-45: 151: 29.27
+	Hs
		242289 PRAF2_HUMAN (1-178): 4.96e-71: 214: 100.00		REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07
+	Hs
		1310096 PRAF1_HUMAN (5-140): 2.38e-37: 128: 22.79		REEP2_HUMAN (54-176): 1.22e-48: 160: 34.15
+	Dm
		52861 A1Z823_DROME (8-156): 8.11e-13: 65.4: 20.13		A1Z9M2_DROME (4-163): 1.81e-68: 208: 47.83
+	Dm
		52864 A1Z823_DROME (8-156): 8.11e-13: 65.4: 20.13		F2FB55_DROME (32-163): 1.93e-57: 179: 52.27
+	Dm
		52889 A1Z823_DROME (8-156): 8.11e-13: 65.4: 20.13		Q9W1J5_DROME (50-182): 4.19e-37: 131: 25.37