HitPredict

Interactor 1: TRI13 (O60858)
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)
Gene: TRIM13

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 1367
+	Hs
		242800 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Hs
		411414 TRI72_HUMAN (3-291): 9.17e-58: 198: 22.67		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Mm
		546271 TRI72_MOUSE (4-310): 2.16e-53: 186: 19.55		INSR_MOUSE (20-1365): 0: 1219: 56.40
+	Hs
		242813 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87
+	Hs
		242910 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12
+	Hs
		242803 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54
+	Mm
		548981 TR30A_MOUSE (1-301): 3.09e-57: 196: 17.71		NTRK1_MOUSE (977-1262): 5.82e-70: 253: 42.27
+	Hs
		609613 TRI35_HUMAN (2-319): 1.1e-54: 190: 15.34		FGFR3_HUMAN (972-1266): 2.05e-63: 234: 38.44
+	Hs
		665655 TRI54_HUMAN (1-294): 2.78e-56: 190: 20.65		EPHB2_HUMAN (496-674): 6.85e-19: 95.5: 17.88