Protein: OSBL2
Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2)

Gene: OSBL2, OSBPL2
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q9H1P3

Gene Ontology (top 5):
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005811 - lipid droplet
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006699 - bile acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

333190

VAPB
Vesicle-associated membrane protein-associated protein B/C

7

20

Small-scale

0.742

High

1431181

VAPA
Vesicle-associated membrane protein-associated protein A

4

20

Small-scale

0.691

High

1431179

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

2

0

High-throughput

0.602

High

951415

SC61B
Protein transport protein Sec61 subunit beta

2

4

High-throughput

0.584

High

974043

RUXF
Small nuclear ribonucleoprotein F

2

0

High-throughput

0.580

High

327442

ZFPL1
Zinc finger protein-like 1

2

3

High-throughput

0.574

High

1120333

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

1

High-throughput

0.536

High

1431182

RNF14
E3 ubiquitin-protein ligase RNF14

1

6

High-throughput

0.536

High

954413

SNP25
Synaptosomal-associated protein 25

1

7

Small-scale

0.527

High

1200615

Q53XM7
VAMP

1

20

High-throughput

0.515

High

856915

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

508606

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

1389501

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

1

High-throughput

0.489

High

242886

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

710755

EPHA8
Ephrin type-A receptor 8

1

8

High-throughput

0.479

High

783123

ARL2
ADP-ribosylation factor-like protein 2

1

4

High-throughput

0.479

High

783411

TRI23
E3 ubiquitin-protein ligase TRIM23

1

3

High-throughput

0.479

High

886321

ARL4D
ADP-ribosylation factor-like protein 4D

1

15

High-throughput

0.479

High

977826

ACTA
Actin, aortic smooth muscle

1

1

High-throughput

0.479

High

1058647

CKAP4
Cytoskeleton-associated protein 4

1

4

High-throughput

0.479

High

1280491

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

1333991

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1428346

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

12

Small-scale

0.479

High

1431177

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.479

High

1431178

TMT1A
Thiol S-methyltransferase TMT1A

1

3

High-throughput

0.479

High

174086

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.437

High

1255492

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1404198

SEC62
Translocation protein SEC62

1

5

High-throughput

0.437

High

1421125

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.437

High

1431180

OTULL
Inactive ubiquitin thioesterase OTULINL

1

6

High-throughput

0.437

High

399627

VTNC
Vitronectin

1

1

High-throughput

0.407

High

1369632

APBB2
Amyloid beta precursor protein binding family B member 2

3

0

High-throughput

0.347

High

1216398

FAXC
Failed axon connections homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025