HitPredict

Interactor 1: TRI13 (O60858)
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)
Gene: TRIM13

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 191
+	Hs
		242840 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		242836 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		242833 TRI13_HUMAN (1-407): 4.22e-135: 394: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		894081 TRI60_HUMAN (1-335): 9.82e-62: 208: 16.57		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		925375 TRI72_HUMAN (3-291): 9.17e-58: 198: 22.67		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		436393 TRI59_HUMAN (1-314): 2.98e-59: 199: 32.92		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		1183455 TRI59_HUMAN (1-314): 2.98e-59: 199: 32.92		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82