HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 1114
+	Hs
		243277 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		243241 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		243250 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		243251 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		507875 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		338003 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		383639 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		384352 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		243293 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		243425 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		508145 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		609471 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16
+	Hs
		338830 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		383929 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		681463 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		385330 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Mm
		1142038 DNJA3_MOUSE (2-395): 4.22e-117: 351: 25.98		MUSK_MOUSE (396-1016): 3.17e-137: 438: 25.52
+	Hs
		608081 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		681349 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25
+	Hs
		729333 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25