HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	35509820, 35987950, 35256949
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 474
+	Hs
		242738 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		COR1B_HUMAN (2-472): 5.26e-123: 369: 71.73
+	Hs
		240860 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		COR1A_HUMAN (2-467): 2.42e-115: 348: 64.24
+	Hs
		242784 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		KTNB1_HUMAN (28-459): 1.04e-80: 264: 13.21
+	Hs
		1418839 HOIL1_HUMAN (12-448): 3.03e-67: 225: 16.36		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		242544 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Hs
		242477 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		COR2A_HUMAN (4-212): 4.19e-25: 110: 10.46
+	Hs
		241233 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		CORO7_HUMAN (3-203): 6.99e-23: 104: 12.73
+	Hs
		241507 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		241283 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		241812 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		1310775 CUL9_HUMAN (30-463): 4.64e-78: 267: 18.81		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Hs
		335111 ARI2_HUMAN (222-464): 9.66e-64: 215: 20.82		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		335209 ARI2_HUMAN (222-464): 9.66e-64: 215: 20.82		WSB1_HUMAN (145-313): 7.72e-16: 81.3: 22.09
+	Sc
		509727 UBI4P_YEAST (1-229): 3.44e-60: 203: 18.72		CORO_YEAST (2-164): 4.85e-15: 79.6: 12.64