HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26618866, 31324722, 17110338
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0051087 - protein-folding chaperone binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 1480
+	Hs
		528635 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529547 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		279273 DNJB5_HUMAN (6-356): 1.72e-114: 340: 32.42		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529849 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528576 DNJB1_HUMAN (10-356): 4.98e-50: 174: 36.49		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Sc
		633231 MAS5_YEAST (4-412): 6.79e-144: 417: 46.73		YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59