HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 33567268
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 130
+	Hs
		244795 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44
+	Hs
		244848 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A1J_HUMAN (1-128): 1.18e-67: 201: 97.66
+	Hs
		244634 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85
+	Hs
		391554 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00
+	Hs
		1067005 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92
+	Hs
		631492 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85
+	Hs
		1067038 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85
+	Hs
		1066979 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39
+	Hs
		555299 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06
+	Hs
		555470 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06
+	Sc
		392513 RSC1_YEAST (87-841): 2.12e-39: 161: 12.50		H2A2_YEAST (16-128): 1.02e-59: 181: 79.65
+	Sc
		392549 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		H2A2_YEAST (16-128): 1.02e-59: 181: 79.65
+	Sc
		392580 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		H2A2_YEAST (16-128): 1.02e-59: 181: 79.65
+	Hs
		319113 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06
+	Sc
		392189 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		H2A1_YEAST (16-127): 9.92e-53: 164: 80.36
+	Sc
		392211 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		H2A1_YEAST (16-127): 9.92e-53: 164: 80.36
+	Sp
		391996 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		H2A1_SCHPO (1-121): 6.78e-54: 167: 82.93
+	Dm
		950441 Q9V9T4_DROME (254-469): 3.66e-27: 122: 18.52		H2A_DROME (17-125): 3.74e-60: 182: 88.99
+	Sc
		392382 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		H2A2_YEAST (16-128): 1.02e-59: 181: 79.65
+	Sc
		392389 BDF1_YEAST (7-303): 2.12e-26: 118: 17.85		H2A2_YEAST (16-128): 1.02e-59: 181: 79.65