Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4
Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16980611, 17643375, 16109377, 31753913, 31239290, 32416067, 32669118, 30554943, 16109376, 18039861, 19766566, 21555454, 17690245, 24367103, 26659056, 23596302, 24360279 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008353 - RNA polymerase II CTD heptapeptide repeat kinase activity GO:0032968 - positive regulation of transcription elongation by RNA polymerase II and 1 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
