Interactor 1: HUS1 (O60921)
Checkpoint protein HUS1 (hHUS1)
Gene: HUS1

Interactor 2: RAD9A (Q99638)
Cell cycle checkpoint control protein RAD9A (hRAD9) (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A)
Gene: RAD9A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 26186194, 28514442, 10852904, 11340080, 32296183, 9872989, 33961781, 14611806, 10359610, 26088138, 15314187, 12628935, 10777662, 11907025, 11994305, 35271311, 12734188, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid array, two hybrid prey pooling approach, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hus1~Rad9
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0006974 - DNA damage response
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 280
Hs

1 391
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024