Protein: KIF5C
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)

Gene: KIF5C
Organism: Homo sapiens
Interactions: 88
UniProt ID: O60282

Gene Ontology (top 5):
GO:0003777 - microtubule motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005871 - kinesin complex
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

244135

KINH
Kinesin-1 heavy chain

5

16

Small-scale

0.906

High

244153

KIF5A
Kinesin heavy chain isoform 5A

2

17

High-throughput

0.754

High

244145

1433G
14-3-3 protein gamma

5

20

High-throughput

0.718

High

244116

TRAK2
Trafficking kinesin-binding protein 2

4

20

Small-scale

0.702

High

244149

1433F
14-3-3 protein eta

4

20

High-throughput

0.697

High

244152

KLC1
Kinesin light chain 1

4

20

Small-scale

0.691

High

244134

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.687

High

244158

TRIP6
Thyroid receptor-interacting protein 6

3

4

High-throughput

0.667

High

244133

1433T
14-3-3 protein theta

3

20

High-throughput

0.657

High

244190

EXOC1
Exocyst complex component 1

2

4

High-throughput

0.628

High

171798

AZIN1
Antizyme inhibitor 1

2

1

High-throughput

0.611

High

244125

TAU
Microtubule-associated protein tau

2

12

High-throughput

0.611

High

244185

KLC2
Kinesin light chain 2

2

20

Small-scale

0.611

High

244175

SYNE4
Nesprin-4

3

2

High-throughput

0.609

High

244146

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.601

High

244131

CSK22
Casein kinase II subunit alpha'

1

4

Small-scale

0.586

High

244148

CSK21
Casein kinase II subunit alpha

1

4

Small-scale

0.586

High

244127

MYCL
Protein L-Myc

2

9

High-throughput

0.574

High

244196

COG6
Conserved oligomeric Golgi complex subunit 6

2

2

High-throughput

0.574

High

244195

TRAK1
Trafficking kinesin-binding protein 1

2

18

Small-scale

0.571

High

244183

ANR27
Ankyrin repeat domain-containing protein 27

1

4

Small-scale

0.553

High

244120

PCNT
Pericentrin

1

6

High-throughput

0.541

High

244159

ITSN1
Intersectin-1

1

2

High-throughput

0.541

High

244132

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

8

High-throughput

0.536

High

244137

NUP62
Nuclear pore glycoprotein p62

1

6

High-throughput

0.536

High

244155

CUL1
Cullin-1

1

7

High-throughput

0.536

High

244161

INSY1
Inhibitory synaptic factor 1

1

4

High-throughput

0.536

High

244165

KLC3
Kinesin light chain 3

1

20

High-throughput

0.536

High

244169

TLK2
Serine/threonine-protein kinase tousled-like 2

1

3

High-throughput

0.536

High

244189

KLC4
Kinesin light chain 4

1

20

High-throughput

0.536

High

244119

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.518

High

244178

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

244174

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

244177

BRK1
Protein BRICK1

1

3

High-throughput

0.489

High

244179

HVCN1
Voltage-gated hydrogen channel 1

1

1

High-throughput

0.489

High

244141

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.481

High

244117

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

244118

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

244121

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

3

High-throughput

0.479

High

244122

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.479

High

244123

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

244124

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

244126

FGFR1
Fibroblast growth factor receptor 1

1

11

High-throughput

0.479

High

244128

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.479

High

244129

EZRI
Ezrin

1

3

High-throughput

0.479

High

244130

EGR1
Early growth response protein 1

1

4

High-throughput

0.479

High

244139

TCPE
T-complex protein 1 subunit epsilon

1

7

High-throughput

0.479

High

244140

RBP2
E3 SUMO-protein ligase RanBP2

1

5

Small-scale

0.479

High

244166

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.479

High

244167

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

244171

HOME1
Homer protein homolog 1

1

2

High-throughput

0.479

High

244172

LMTK2
Serine/threonine-protein kinase LMTK2

1

15

High-throughput

0.479

High

244193

HOOK1
Protein Hook homolog 1

1

6

High-throughput

0.479

High

244173

MIRO1
Mitochondrial Rho GTPase 1

1

4

Small-scale

0.470

High

244164

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

244142

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

244147

CSK2B
Casein kinase II subunit beta

1

0

Small-scale

0.458

High

244151

FMR1
Fragile X messenger ribonucleoprotein 1

1

16

High-throughput

0.457

High

244188

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

244194

TNIK
TRAF2 and NCK-interacting protein kinase

1

9

High-throughput

0.457

High

244144

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.445

High

244156

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

244163

CP135
Centrosomal protein of 135 kDa

1

4

High-throughput

0.445

High

104913

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

163666

TCRG1
Transcription elongation regulator 1

1

2

High-throughput

0.437

High

217572

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

244138

MAGA3
Melanoma-associated antigen 3

1

5

Small-scale

0.437

High

244143

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.437

High

244150

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

9

High-throughput

0.437

High

244154

TIF1B
Transcription intermediary factor 1-beta

1

17

High-throughput

0.437

High

244157

EEA1
Early endosome antigen 1

1

4

High-throughput

0.437

High

244160

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

244162

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

9

High-throughput

0.437

High

244170

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

9

High-throughput

0.437

High

244187

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

2

High-throughput

0.437

High

244197

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.437

High

244199

KPTN
KICSTOR complex protein kaptin

1

1

High-throughput

0.437

High

244136

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.407

High

244168

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.407

High

244180

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

244182

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.407

High

244192

S53A1
Solute carrier family 53 member 1

1

1

High-throughput

0.407

High

244198

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

2

High-throughput

0.407

High

244181

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low

244184

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

244186

HES4
Transcription factor HES-4

1

0

High-throughput

0.249

Low

244191

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.249

Low

244176

MOT10
Monocarboxylate transporter 10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025