HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 221
+	Hs
		244481 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Mm
		1143313 BRD4_MOUSE (1-1362): 1.55e-108: 377: 89.93		SRSF2_MOUSE (1-221): 1.22e-43: 147: 100.00
+	Hs
		245064 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76