HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SRSF9 (Q13242)
Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)
Gene: SRSF9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31239290, 32416067, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 221
+	Hs
		244340 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		244381 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Hs
		244481 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SF3B4_HUMAN (1-211): 2.82e-49: 167: 15.32
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		244886 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RBM4_HUMAN (110-185): 1.92e-16: 78.8: 18.42
+	Hs
		992783 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		631419 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		SRSF9_HUMAN (1-221): 1.6e-55: 178: 100.00
+	Hs
		1028552 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SRSF9_HUMAN (1-221): 1.6e-55: 178: 100.00
+	Zm
		19361 A0A1D6HCG5_MAIZE (43-242): 1.58e-37: 153: 25.00		Q64HC3_MAIZE (16-189): 3.04e-61: 194: 50.81
+	Sc
		965476 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		NOP3_YEAST (7-179): 6.54e-38: 137: 27.68
+	Hs
		1028563 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		SRSF9_HUMAN (1-221): 1.6e-55: 178: 100.00
+	Sc
		715372 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		NOP3_YEAST (7-179): 6.54e-38: 137: 27.68