HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1140
+	Hs
		1082309 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		1082298 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Hs
		244478 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SF3B3_HUMAN (3-1126): 0: 1102: 21.33
+	Hs
		1082415 BRWD1_HUMAN (295-501): 2.62e-13: 77.5: 16.91		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Mm
		1112292 BRWD1_MOUSE (23-374): 2.04e-10: 67.8: 8.79		DDB1_MOUSE (1-1140): 0: 1422: 99.65
+	Hs
		1073091 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		SF3B3_HUMAN (3-1126): 0: 1102: 21.33
+	Hs
		1073090 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		SF3B3_HUMAN (3-1126): 0: 1102: 21.33
+	Hs
		244349 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87
+	Sc
		715398 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		CFT1_YEAST (11-1125): 0: 678: 14.79