HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 551
+	Hs
		244138 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		244665 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		244139 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		245076 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MYO15_HUMAN (192-426): 1.17e-19: 95.8: 20.16
+	Hs
		244869 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Hs
		244908 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69
+	Hs
		631379 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		846778 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		631380 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		846977 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		846993 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		846838 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		846812 PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Dm
		631317 Q9VC36_DROME (76-150): 1.69e-18: 94.4: 33.33		BRM_DROME (249-551): 1.19e-45: 175: 20.72
+	Hs
		847007 PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Mm
		101535 F8VQD1_MOUSE (15-956): 3.46e-18: 93.2: 10.61		SMCA2_MOUSE (137-551): 5.16e-46: 175: 14.44
+	Hs
		847033 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Mm
		1111945 PB1_MOUSE (9-629): 2.51e-37: 156: 12.50		SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30
+	Mm
		101533 F8VQD1_MOUSE (15-956): 3.46e-18: 93.2: 10.61		SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30