HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	32416067, 26659056
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 582
+	Hs
		631451 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1066985 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		243792 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		244894 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		244584 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		244491 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		631575 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1067122 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1262793 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Rn
		78192 Q6AYL3_RAT (336-590): 5.88e-18: 88.6: 22.75		ELAV1_RAT (92-211): 6.43e-13: 71.9: 22.50