Protein: RPGP1
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)

Gene: RPGP1, RAP1GAP
Organism: Homo sapiens
Interactions: 48
UniProt ID: P47736

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475915

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

4

4

High-throughput

0.892

High

866526

RPGP2
Rap1 GTPase-activating protein 2

1

8

High-throughput

0.691

High

866516

RAP1B
Ras-related protein Rap-1b

1

14

Small-scale

0.665

High

618439

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

4

Small-scale

0.647

High

866519

RAP1A
Ras-related protein Rap-1A

1

14

Small-scale

0.647

High

866520

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.584

High

703488

MK01
Mitogen-activated protein kinase 1

2

4

High-throughput

0.571

High

866512

PLK1
Serine/threonine-protein kinase PLK1

1

3

Small-scale

0.561

High

866514

AFAD
Afadin

1

15

Small-scale

0.552

High

762425

PROF2
Profilin-2

1

1

High-throughput

0.541

High

866527

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.541

High

281724

VP26A
Vacuolar protein sorting-associated protein 26A

1

2

High-throughput

0.536

High

286762

SKAP2
Src kinase-associated phosphoprotein 2

1

5

High-throughput

0.536

High

332289

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.513

High

529309

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

561113

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.513

High

866513

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

866533

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

866534

ZN330
Zinc finger protein 330

1

0

High-throughput

0.513

High

156604

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

2

High-throughput

0.508

High

866521

KC1G2
Casein kinase I isoform gamma-2

1

1

High-throughput

0.508

High

866525

MK06
Mitogen-activated protein kinase 6

1

5

High-throughput

0.508

High

443256

CDK1
Cyclin-dependent kinase 1

1

2

Small-scale

0.501

High

578420

BRAF
Serine/threonine-protein kinase B-raf

1

3

Small-scale

0.501

High

171059

VP26C
Vacuolar protein sorting-associated protein 26C

1

2

High-throughput

0.494

High

866524

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.493

High

159955

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

167236

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

866529

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.486

High

50391

MEX3A
RNA-binding protein MEX3A

1

2

Small-scale

0.479

High

172563

XPO1
Exportin-1

1

2

High-throughput

0.479

High

413389

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

563395

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.479

High

638882

CNR1
Cannabinoid receptor 1

1

1

Small-scale

0.479

High

690820

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

729671

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

730443

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

866517

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

866518

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.479

High

866522

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

866523

UBE3A
Ubiquitin-protein ligase E3A

1

3

Small-scale

0.479

High

866530

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

866531

FBW1B
F-box/WD repeat-containing protein 11

1

4

Small-scale

0.479

High

866532

FBW1A
F-box/WD repeat-containing protein 1A

1

4

Small-scale

0.479

High

105536

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

866528

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

767648

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

866515

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025