HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 245
+	Hs
		245134 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RN114_HUMAN (16-241): 4.34e-36: 129: 30.53
+	Hs
		243914 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RO52_HUMAN (6-157): 6.92e-32: 123: 17.11
+	Hs
		244773 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TRI11_HUMAN (9-171): 4.13e-29: 115: 12.50
+	Hs
		244904 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TRIM4_HUMAN (10-142): 6.25e-29: 115: 13.33
+	Hs
		244834 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		244333 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Hs
		631409 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Mm
		101543 F8VQD1_MOUSE (15-956): 3.46e-18: 93.2: 10.61		RN138_MOUSE (1-245): 1.2e-56: 182: 93.88
+	Hs
		319384 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		PZRN3_HUMAN (1-164): 4.32e-25: 105: 18.79
+	Hs
		1262804 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Pf
		1211846 Q8IB67_PLAF7 (141-455): 1.37e-29: 130: 15.64		Q8I5Z0_PLAF7 (9-61): 8.66e-10: 60.7: 37.74