HitPredict

Interactor 1: NSMA (O60906)
Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Lyso-platelet-activating factor-phospholipase C) (Lyso-PAF-PLC) (Neutral sphingomyelinase) (N-SMase) (nSMase) (nSMase1)
Gene: SMPD2

Interactor 2: PCDGG (Q9UN71)
Protocadherin gamma-B4 (PCDH-gamma-B4) (Cadherin-20) (Fibroblast cadherin-2)
Gene: PCDHGB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 923
+	Hs
		245538 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDGE_HUMAN (32-908): 0: 1020: 71.19
+	Hs
		245536 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDB7_HUMAN (12-766): 0: 593: 44.60
+	Hs
		245540 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDA3_HUMAN (3-439): 1.25e-98: 332: 26.90
+	Hs
		245542 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDC2_HUMAN (4-442): 1.32e-97: 330: 27.73
+	Hs
		245537 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDGL_HUMAN (3-441): 2.92e-94: 320: 25.82
+	Hs
		245539 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDG5_HUMAN (1-337): 1e-63: 234: 24.72
+	Hs
		245520 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDBG_HUMAN (1-370): 8.67e-61: 223: 22.74
+	Hs
		245541 NSMA_HUMAN (1-423): 0: 736: 100.00		PCDAB_HUMAN (2-233): 2.5e-36: 150: 19.92