HitPredict

Interactor 1: TBL1X (O60907)
F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked)
Gene: TBL1X

Interactor 2: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 27880911, 18374649, 18202150, 21258344
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains LisH~LisH, WD40~WD40
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 577
Hs

1 514
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Last updated: 15 Jul 2024