HitPredict

Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: TERF2 (Q15554)
Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
Gene: TERF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

The method score is based on:

Property	Details
Experiments	10888888, 28216226, 19287395
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031848 - protection from non-homologous end joining at telomere and 2 others more... GO:0032206 - positive regulation of telomere maintenance GO:1904354 - negative regulation of telomere capping
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	754
Hs

1	542

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024