HitPredict

Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25533185, 37071664
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0000781 - chromosome, telomeric region GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0032206 - positive regulation of telomere maintenance and 1 others more... GO:0090656 - t-circle formation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 754 Hs			1 1834
+	Hs
		246226 NBN_HUMAN (1-754): 0: 1078: 100.00		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54