Interactor 1: O61380 (O61380)
Eukaryotic translation initiation factor 4G1, isoform A (Eukaryotic translation initiation factor 4G1, isoform C) (FI02056p) (Translation initiation factor eIF4G)
Gene: eIF4G1

Interactor 2: IF4E (P48598)
Eukaryotic translation initiation factor 4E1 (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: eIF4E1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 15465908, 23716590, 25179781, 27773676, 9578457, 27374989, 15804566, 19268617, 8027064, 17611220, 22833128, 25849588, 14760701, 28875934, 14685270
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, two hybrid
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000340 - RNA 7-methylguanosine cap binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0006412 - translation
GO:0006413 - translational initiation
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1666
Dm

1 259
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ At
+ Ce
+ At
+ At
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024