HitPredict

Interactor 1: ERGO1 (O61931)
Piwi-like protein ergo-1 (Endogenous RNA interference deficient argonaute protein 1)
Gene: ergo-1

Interactor 2: LIN41 (Q9U489)
Protein lin-41 (Abnormal cell lineage protein 41)
Gene: lin-41

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28576864
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0035198 - miRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1121 Ce			1 1147
+	Ce
		108593 G5EGR6_CAEEL (125-1115): 0: 843: 20.92		LIN41_CAEEL (1-1147): 0: 1087: 100.00
+	Ce
		953796 P90786_CAEEL (474-1080): 7.15e-95: 323: 19.78		LIN41_CAEEL (1-1147): 0: 1087: 100.00
+	Mm
		1093411 AGO2_MOUSE (151-1109): 0: 883: 21.59		LIN41_MOUSE (365-1147): 3.79e-125: 406: 31.94
+	Hs
		1102507 AGO2_HUMAN (165-1109): 0: 875: 21.70		LIN41_HUMAN (349-1147): 1.44e-127: 413: 32.30
+	Hs
		585070 AGO3_HUMAN (156-1109): 0: 858: 20.40		RO52_HUMAN (357-848): 1.73e-81: 276: 11.51
+	Hs
		585074 AGO4_HUMAN (158-1110): 0: 846: 20.70		RO52_HUMAN (357-848): 1.73e-81: 276: 11.51
+	Hs
		1282069 AGO2_HUMAN (165-1109): 0: 875: 21.70		TRI63_HUMAN (361-673): 7.46e-59: 208: 15.18
+	Hs
		1317538 AGO2_HUMAN (165-1109): 0: 875: 21.70		TRI55_HUMAN (366-673): 6.7e-49: 185: 12.99
+	Dm
		1103832 Q32KD4_DROME (130-1110): 0: 848: 21.44		WECH_DROME (927-1147): 3.56e-36: 150: 27.78
+	Dm
		1100038 Q27IR0_DROME (130-1076): 0: 842: 21.80		WECH_DROME (927-1147): 3.56e-36: 150: 27.78
+	Mm
		1208468 AGO1_MOUSE (167-1109): 0: 863: 21.44		TRI32_MOUSE (878-1147): 2.31e-29: 127: 23.26
+	Dm
		1103862 Q32KD4_DROME (130-1110): 0: 848: 21.44		Q9W378_DROME (971-1147): 5.1e-26: 118: 22.10
+	Hs
		170508 AGO2_HUMAN (165-1109): 0: 875: 21.70		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1100039 Q27IR0_DROME (130-1076): 0: 842: 21.80		Q9W378_DROME (971-1147): 5.1e-26: 118: 22.10
+	Hs
		170510 AGO1_HUMAN (167-1109): 0: 863: 21.44		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Hs
		170478 AGO3_HUMAN (156-1109): 0: 858: 20.40		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1103819 Q32KD4_DROME (130-1110): 0: 848: 21.44		BRAT_DROME (368-709): 6.28e-17: 88.5: 13.35
+	Hs
		170484 AGO4_HUMAN (158-1110): 0: 846: 20.70		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1100037 Q27IR0_DROME (130-1076): 0: 842: 21.80		BRAT_DROME (368-709): 6.28e-17: 88.5: 13.35
+	Hs
		1294945 PIWL1_HUMAN (243-1093): 0: 642: 17.25		TRI54_HUMAN (366-704): 2.45e-58: 207: 13.54