HitPredict

Interactor 1: O62332 (O62332)
Importin N-terminal domain-containing protein
Gene: imb-2

Interactor 2: Q9XWK3 (Q9XWK3)
Nucleoporin p58/p45
Gene: npp-4

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18692475
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 883 Ce			1 538
+	Hs
		858024 TNPO1_HUMAN (2-883): 0: 591: 51.46		NUP98_HUMAN (38-364): 7.96e-16: 83.1: 16.37
+	Ce
		248176 O62332_CAEEL (1-883): 0: 598: 100.00		Q21295_CAEEL (9-158): 4.2e-12: 70.7: 24.00
+	Ce
		248185 O62332_CAEEL (1-883): 0: 598: 100.00		Q9U3B9_CAEEL (58-277): 3.97e-10: 64.6: 22.03
+	Hs
		155553 TNPO2_HUMAN (1-883): 0: 573: 50.55		NUP98_HUMAN (38-364): 7.96e-16: 83.1: 16.37
+	Hs
		727300 TNPO1_HUMAN (2-883): 0: 591: 51.46		NU214_HUMAN (6-510): 3.95e-10: 65: 11.59
+	Tt
		101907 G0SGZ5_CHATD (1-883): 7.5e-143: 448: 33.30		NU145_CHATD (14-345): 2.65e-10: 65.3: 14.11
+	Xl
		853820 IMB_XENLA (11-857): 2.02e-98: 329: 15.72		Q6DCP4_XENLA (4-360): 1.82e-18: 90.8: 15.08
+	Sc
		746532 IMB2_YEAST (2-864): 1.01e-100: 336: 28.56		NUP49_YEAST (5-326): 2.73e-14: 77.3: 17.98
+	Sc
		746520 IMB2_YEAST (2-864): 1.01e-100: 336: 28.56		NU145_YEAST (82-440): 1.22e-12: 73: 13.41
+	Sc
		746518 IMB2_YEAST (2-864): 1.01e-100: 336: 28.56		NUP57_YEAST (11-220): 1.82e-12: 71.9: 25.46
+	Sc
		746534 IMB2_YEAST (2-864): 1.01e-100: 336: 28.56		NU116_YEAST (38-517): 4.84e-10: 64.6: 13.97
+	Sc
		746533 IMB2_YEAST (2-864): 1.01e-100: 336: 28.56		NU100_YEAST (32-535): 2.6e-09: 62.3: 13.50
+	Sc
		969363 IMB1_YEAST (12-825): 2.12e-90: 307: 17.19		NUP49_YEAST (5-326): 2.73e-14: 77.3: 17.98
+	Sc
		830681 IMB1_YEAST (12-825): 2.12e-90: 307: 17.19		NU145_YEAST (82-440): 1.22e-12: 73: 13.41
+	Sc
		774378 IMB1_YEAST (12-825): 2.12e-90: 307: 17.19		NU159_YEAST (2-485): 1.45e-12: 72.7: 12.91
+	Sc
		823006 IMB1_YEAST (12-825): 2.12e-90: 307: 17.19		NUP57_YEAST (11-220): 1.82e-12: 71.9: 25.46
+	Sc
		971907 IMB1_YEAST (12-825): 2.12e-90: 307: 17.19		NU116_YEAST (38-517): 4.84e-10: 64.6: 13.97
+	Sc
		971878 IMB1_YEAST (12-825): 2.12e-90: 307: 17.19		NU100_YEAST (32-535): 2.6e-09: 62.3: 13.50
+	Hs
		727228 XPO2_HUMAN (3-806): 7.46e-79: 277: 13.59		NU214_HUMAN (6-510): 3.95e-10: 65: 11.59
+	Ce
		136533 Q9N5V3_CAEEL (10-591): 6.84e-57: 214: 17.89		O01576_CAEEL (5-495): 4.26e-14: 77.3: 18.34