HitPredict

Interactor 1: O62422 (O62422)
Cdc-42 Related Protein
Gene: crp-1

Interactor 2: MIG5 (Q22227)
Segment polarity protein dishevelled homolog mig-5 (Abnormal cell migration protein 5)
Gene: mig-5

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	1.00	0.637

Property	Details
Experiments	14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 187 Ce			1 672
+	Hs
		951208 RHOG_HUMAN (4-187): 1.78e-85: 251: 37.50		DVL3_HUMAN (11-542): 3.89e-112: 355: 24.83
+	Hs
		892678 RAC3_HUMAN (5-183): 2.82e-88: 258: 42.25		NEB1_HUMAN (102-388): 3.59e-35: 145: 15.51
+	Hs
		436569 RHOC_HUMAN (6-187): 1.73e-86: 254: 36.84		NEB1_HUMAN (102-388): 3.59e-35: 145: 15.51
+	Hs
		894581 CDC42_HUMAN (5-186): 7.35e-86: 252: 42.63		NEB1_HUMAN (102-388): 3.59e-35: 145: 15.51
+	Hs
		951455 RHOG_HUMAN (4-187): 1.78e-85: 251: 37.50		NEB1_HUMAN (102-388): 3.59e-35: 145: 15.51
+	Mm
		1111996 Q3TLP8_MOUSE (5-186): 1e-88: 260: 38.76		DLG4_MOUSE (163-457): 6.27e-21: 99.7: 15.26
+	Hs
		892525 RAC3_HUMAN (5-183): 2.82e-88: 258: 42.25		DLG3_HUMAN (109-296): 9.49e-16: 83.2: 19.80
+	Hs
		951207 RHOG_HUMAN (4-187): 1.78e-85: 251: 37.50		DLG3_HUMAN (109-296): 9.49e-16: 83.2: 19.80
+	Hs
		892341 RAC3_HUMAN (5-183): 2.82e-88: 258: 42.25		DLG1_HUMAN (173-314): 3.24e-13: 75.1: 15.17
+	Hs
		876341 CDC42_HUMAN (5-186): 7.35e-86: 252: 42.63		AFAD_HUMAN (220-423): 2.41e-14: 79.2: 17.62
+	Hs
		436278 RHOC_HUMAN (6-187): 1.73e-86: 254: 36.84		DLG1_HUMAN (173-314): 3.24e-13: 75.1: 15.17
+	Hs
		892339 RAC3_HUMAN (5-183): 2.82e-88: 258: 42.25		PTN13_HUMAN (169-404): 1.31e-11: 70.5: 13.82
+	Hs
		436419 RHOC_HUMAN (6-187): 1.73e-86: 254: 36.84		LNX1_HUMAN (46-305): 6.13e-13: 74.2: 14.04
+	Hs
		893948 CDC42_HUMAN (5-186): 7.35e-86: 252: 42.63		DLG1_HUMAN (173-314): 3.24e-13: 75.1: 15.17
+	Hs
		950954 RHOG_HUMAN (4-187): 1.78e-85: 251: 37.50		DLG1_HUMAN (173-314): 3.24e-13: 75.1: 15.17
+	Hs
		436277 RHOC_HUMAN (6-187): 1.73e-86: 254: 36.84		PTN13_HUMAN (169-404): 1.31e-11: 70.5: 13.82
+	Hs
		893945 CDC42_HUMAN (5-186): 7.35e-86: 252: 42.63		PTN13_HUMAN (169-404): 1.31e-11: 70.5: 13.82
+	Mm
		925797 RAC1_MOUSE (5-187): 9.45e-74: 221: 42.41		DLG4_MOUSE (163-457): 6.27e-21: 99.7: 15.26
+	Hs
		436557 RHOC_HUMAN (6-187): 1.73e-86: 254: 36.84		ZO2_HUMAN (203-410): 2.24e-10: 66.1: 13.36
+	Hs
		914039 RB11A_HUMAN (2-182): 2.81e-73: 221: 26.92		DLG1_HUMAN (173-314): 3.24e-13: 75.1: 15.17