Protein: NDK8
Putative nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6)

Gene: NDK8, NME2P1
Organism: Homo sapiens
Interactions: 83
UniProt ID: O60361

Gene Ontology (top 5):
GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006183 - GTP biosynthetic process
GO:0006228 - UTP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

248192

NDKA
Nucleoside diphosphate kinase A

2

17

High-throughput

0.712

High

248209

NDK3
Nucleoside diphosphate kinase 3

2

16

High-throughput

0.712

High

248195

NDKB
Nucleoside diphosphate kinase B

1

17

High-throughput

0.575

High

248214

Q32Q12
Nucleoside diphosphate kinase

1

16

High-throughput

0.575

High

248218

TMM53
Transmembrane protein 53

2

0

High-throughput

0.559

High

248254

UB2J1
Ubiquitin-conjugating enzyme E2 J1

2

0

High-throughput

0.559

High

248186

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

3

High-throughput

0.552

High

248198

IKBA
NF-kappa-B inhibitor alpha

2

2

High-throughput

0.552

High

248204

NPC2
NPC intracellular cholesterol transporter 2

2

3

High-throughput

0.552

High

248219

FOXR2
Forkhead box protein R2

2

1

High-throughput

0.552

High

248225

CLRN3
Clarin-3

2

0

High-throughput

0.547

High

248197

UCP1
Mitochondrial brown fat uncoupling protein 1

2

1

High-throughput

0.533

High

248230

S2536
Solute carrier family 25 member 36

2

2

High-throughput

0.533

High

248194

KCRS
Creatine kinase S-type, mitochondrial

2

0

High-throughput

0.528

High

248196

NFYA
Nuclear transcription factor Y subunit alpha

2

0

High-throughput

0.528

High

248220

SETX
Probable helicase senataxin

2

0

High-throughput

0.528

High

248251

MBD5
Methyl-CpG-binding domain protein 5

2

0

High-throughput

0.528

High

162995

H17B6
17-beta-hydroxysteroid dehydrogenase type 6

2

2

High-throughput

0.504

High

248181

OR5F1
Olfactory receptor 5F1

2

1

High-throughput

0.504

High

248226

CTL5
Choline transporter-like protein 5

2

2

High-throughput

0.504

High

248227

OR2K2
Olfactory receptor 2K2

2

2

High-throughput

0.504

High

248229

RDH5
Retinol dehydrogenase 5

2

2

High-throughput

0.504

High

248237

RDH12
Retinol dehydrogenase 12

2

2

High-throughput

0.504

High

248240

RNF26
E3 ubiquitin-protein ligase RNF26

2

1

High-throughput

0.504

High

248243

P2Y12
P2Y purinoceptor 12

2

1

High-throughput

0.504

High

248221

STRA8
Stimulated by retinoic acid gene 8 protein homolog

1

0

High-throughput

0.458

High

85089

B7Z207
Protein-serine/threonine kinase

1

2

High-throughput

0.445

High

248180

VAMP5
Vesicle-associated membrane protein 5

1

1

High-throughput

0.445

High

248184

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.445

High

248187

S10A9
Protein S100-A9

1

2

High-throughput

0.445

High

248188

FABPL
Fatty acid-binding protein, liver

1

3

High-throughput

0.445

High

248190

CO6A2

1

2

High-throughput

0.445

High

248193

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

1

High-throughput

0.445

High

248205

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.445

High

248207

TBB4B
Tubulin beta-4B chain

1

6

High-throughput

0.445

High

248208

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.445

High

248211

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.445

High

248212

DUS5
Dual specificity protein phosphatase 5

1

6

High-throughput

0.445

High

248239

TBB2B
Tubulin beta-2B chain

1

6

High-throughput

0.445

High

85174

B7Z613
Glycoprotein M6B

1

1

High-throughput

0.437

High

158955

GP171
G-protein coupled receptor 171

1

1

High-throughput

0.437

High

166820

MGST3
Glutathione S-transferase 3, mitochondrial

1

1

High-throughput

0.437

High

248210

GPM6B
Neuronal membrane glycoprotein M6-b

1

1

High-throughput

0.437

High

248217

OR2T2
Olfactory receptor 2T2

1

2

High-throughput

0.437

High

248248

DDIT4
DNA damage-inducible transcript 4 protein

1

1

High-throughput

0.437

High

248191

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

0

High-throughput

0.426

High

248242

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.426

High

248253

MO4L1
Mortality factor 4-like protein 1

1

0

High-throughput

0.426

High

212747

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

3

High-throughput

0.407

High

248203

TPD52
Tumor protein D52

1

1

High-throughput

0.407

High

248206

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.407

High

248228

RN133
E3 ubiquitin-protein ligase RNF133

1

3

High-throughput

0.407

High

248234

S2544
Solute carrier family 25 member 44

1

1

High-throughput

0.407

High

248245

BIN3
Bridging integrator 3

1

1

High-throughput

0.407

High

248246

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.407

High

248249

OCAD1
OCIA domain-containing protein 1

1

3

High-throughput

0.407

High

248182

LRAT
Lecithin retinol acyltransferase

2

0

High-throughput

0.305

High

248238

ATX2
Ataxin-2

2

0

High-throughput

0.298

High

248250

S39A1
Zinc transporter ZIP1

2

0

High-throughput

0.298

High

248183

RPP29
Ribonuclease P protein subunit p29

2

0

High-throughput

0.288

High

248185

GAST
Gastrin [Cleaved into: Gastrin-71

2

0

High-throughput

0.288

High

248216

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

2

0

High-throughput

0.288

High

248223

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

2

0

High-throughput

0.288

High

248224

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

2

0

High-throughput

0.288

High

248233

CK024
Uncharacterized protein C11orf24

2

0

High-throughput

0.288

High

248189

NARR
Ras-related protein Rab-34, isoform NARR

1

0

High-throughput

0.249

Low

248215

MOGT2
2-acylglycerol O-acyltransferase 2

1

0

High-throughput

0.249

Low

248222

VASH2
Tubulinyl-Tyr carboxypeptidase 2

1

0

High-throughput

0.249

Low

248179

STC2
Stanniocalcin-2

1

0

High-throughput

0.232

Low

248199

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.232

Low

248200

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

0

High-throughput

0.232

Low

248201

CASP4
Caspase-4

1

0

High-throughput

0.232

Low

248202

EFNA5
Ephrin-A5

1

0

High-throughput

0.232

Low

248213

DB110
Beta-defensin 110

1

0

High-throughput

0.232

Low

248231

APC16
Anaphase-promoting complex subunit 16

1

0

High-throughput

0.232

Low

248232

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.232

Low

248235

F227B
Protein FAM227B

1

0

High-throughput

0.232

Low

248236

F218A
Protein FAM218A

1

0

High-throughput

0.232

Low

248241

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.232

Low

248244

E41LA
Band 4.1-like protein 4A

1

0

High-throughput

0.232

Low

248247

S52A1
Solute carrier family 52, riboflavin transporter, member 1

1

0

High-throughput

0.232

Low

248252

KAAG1
Kidney-associated antigen 1

1

0

High-throughput

0.232

Low

248255

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025