HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: 1433G (P61982)
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: Ywhag

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27889896
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Mm			1 247
+	Mm
		250606 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Mm
		250656 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Mm
		250609 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		1433T_MOUSE (2-245): 3e-105: 306: 70.73
+	Hs
		927328 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Mm
		905355 LNX2_MOUSE (4-728): 1.69e-87: 291: 38.25		1433G_MOUSE (1-247): 3.15e-139: 392: 100.00
+	Hs
		684204 LNX2_HUMAN (5-728): 2.59e-111: 354: 45.77		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Mm
		926859 LNX2_MOUSE (4-728): 1.69e-87: 291: 38.25		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		904552 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982003 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		910195 GRIP1_HUMAN (131-464): 5.32e-26: 116: 18.97		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		905296 GRIP1_HUMAN (131-464): 5.32e-26: 116: 18.97		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Ce
		88195 D3YT29_CAEEL (166-726): 2.41e-46: 179: 14.51		14331_CAEEL (5-246): 2.81e-103: 301: 75.31
+	Hs
		683339 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927034 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646881 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683846 GRIP1_HUMAN (131-464): 5.32e-26: 116: 18.97		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		684030 SCRIB_HUMAN (230-597): 2.22e-32: 137: 20.10		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		647412 GRIP1_HUMAN (131-464): 5.32e-26: 116: 18.97		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Mm
		250875 PARD3_MOUSE (206-469): 1.02e-30: 131: 21.52		1433S_MOUSE (2-236): 1.38e-95: 281: 65.96
+	Hs
		684417 GRIP1_HUMAN (131-464): 5.32e-26: 116: 18.97		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16