HitPredict

Interactor 1: PRGC1 (O70343)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha) (PPAR-gamma coactivator 1-alpha) (PPARGC-1-alpha)
Gene: Ppargc1a

Interactor 2: MED1 (Q925J9)
Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2)
Gene: MED1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

The method score is based on:

Property	Details
Experiments	25644604
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0003712 - transcription coregulator activity GO:0003713 - transcription coactivator activity and 12 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0010628 - positive regulation of gene expression GO:0030331 - nuclear estrogen receptor binding GO:0030374 - nuclear receptor coactivator activity GO:0031490 - chromatin DNA binding GO:0042975 - peroxisome proliferator activated receptor binding GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0097067 - cellular response to thyroid hormone stimulus GO:1990841 - promoter-specific chromatin binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	797
Mm

1	1575

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Last updated: 15 Jul 2024