HitPredict

Interactor 1: SMAD2 (O70436)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (SMAD family member 2) (SMAD 2) (Smad2)
Gene: SMAD2

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14507671
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 467 Rn			1 810
+	Hs
		475814 SMAD2_HUMAN (1-467): 0: 675: 99.36		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475623 SMAD3_HUMAN (1-467): 0: 617: 83.73		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475815 SMAD1_HUMAN (1-467): 0: 570: 55.53		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475717 SMAD4_HUMAN (11-456): 8.74e-148: 434: 30.88		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		1078562 SMAD2_HUMAN (1-467): 0: 675: 99.36		Q5RKT7_HUMAN (685-760): 2.68e-42: 152: 100.00
+	Hs
		924009 SMAD2_HUMAN (1-467): 0: 675: 99.36		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		397950 SMAD4_HUMAN (11-456): 8.74e-148: 434: 30.88		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69