HitPredict

Interactor 1: 1433S (O70456)
14-3-3 protein sigma (Stratifin)
Gene: Sfn

Interactor 2: HDAC5 (Q9Z2V6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Histone deacetylase mHDA1)
Gene: HDAC5

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	31040226
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Mm			1 1113
+	Mm
		250870 1433S_MOUSE (1-248): 3.26e-157: 437: 100.00		Q3UJF1_MOUSE (1-1113): 0: 711: 99.28
+	Mm
		910352 1433E_MOUSE (2-247): 1.43e-147: 413: 59.35		HDAC5_MOUSE (1-1113): 0: 721: 100.00
+	Mm
		910239 1433E_MOUSE (2-247): 1.43e-147: 413: 59.35		Q3UJF1_MOUSE (1-1113): 0: 711: 99.28
+	Hs
		684405 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC5_HUMAN (1-1113): 0: 686: 92.79
+	Hs
		910173 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC5_HUMAN (1-1113): 0: 686: 92.79
+	Hs
		683923 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC4_HUMAN (1-1093): 0: 639: 55.65
+	Hs
		880661 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC4_HUMAN (1-1093): 0: 639: 55.65
+	Hs
		684387 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC9_HUMAN (25-1046): 0: 595: 54.28
+	Hs
		910144 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC9_HUMAN (25-1046): 0: 595: 54.28
+	Dm
		664611 1433Z_DROME (1-240): 3.49e-136: 384: 65.83		Q59E49_DROME (76-1112): 0: 590: 31.67
+	Hs
		646756 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		HDAC4_HUMAN (1-1093): 0: 639: 55.65
+	Hs
		684233 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC7_HUMAN (111-1113): 3.75e-162: 506: 41.19
+	Hs
		909856 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC7_HUMAN (111-1113): 3.75e-162: 506: 41.19
+	Hs
		909530 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC1_HUMAN (664-1070): 8.93e-160: 484: 21.85
+	Hs
		177251 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC3_HUMAN (670-1110): 9e-150: 456: 21.13
+	Dm
		664668 1433Z_DROME (1-240): 3.49e-136: 384: 65.83		Q9VYF3_DROME (91-1112): 3.54e-142: 461: 29.48
+	At
		817061 14310_ARATH (2-247): 8.73e-138: 388: 54.03		HDA5_ARATH (669-1112): 2.57e-142: 445: 33.11
+	Hs
		910121 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC6_HUMAN (609-1059): 6.37e-110: 373: 31.77
+	Hs
		177204 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		HDAC3_HUMAN (670-1110): 9e-150: 456: 21.13
+	Mm
		910299 1433E_MOUSE (2-247): 1.43e-147: 413: 59.35		HDAC7_MOUSE (41-585): 2.61e-32: 138: 19.40