Protein: PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)

Gene: PP4C, PPP4C
Organism: Homo sapiens
Interactions: 125
UniProt ID: P60510

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000785 - chromatin
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

890950

IGBP1
Immunoglobulin-binding protein 1

11

19

Small-scale

0.981

High

890987

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

8

19

Small-scale

0.974

High

672060

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

6

20

Small-scale

0.956

High

272423

TIPRL
TIP41-like protein

5

6

Small-scale

0.927

High

890964

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

4

20

Small-scale

0.909

High

890944

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

4

12

High-throughput

0.906

High

890966

PTPA
Serine/threonine-protein phosphatase 2A activator

2

10

High-throughput

0.789

High

891011

LCMT1
Leucine carboxyl methyltransferase 1

2

1

High-throughput

0.789

High

891018

PPME1
Protein phosphatase methylesterase 1

2

3

High-throughput

0.789

High

891008

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

13

1

Small-scale

0.765

High

890978

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

11

5

Small-scale

0.761

High

890973

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

8

5

Small-scale

0.752

High

890970

CCDC6
Coiled-coil domain-containing protein 6

6

17

Small-scale

0.740

High

890979

PP4R4
Serine/threonine-protein phosphatase 4 regulatory subunit 4

5

20

Small-scale

0.728

High

890977

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

4

19

High-throughput

0.706

High

573192

TCPA
T-complex protein 1 subunit alpha

4

20

Small-scale

0.704

High

770761

TCPZ
T-complex protein 1 subunit zeta

4

20

Small-scale

0.704

High

821143

TCPE
T-complex protein 1 subunit epsilon

4

20

Small-scale

0.704

High

826591

TCPG
T-complex protein 1 subunit gamma

4

20

Small-scale

0.704

High

843130

TCPD
T-complex protein 1 subunit delta

4

20

Small-scale

0.704

High

890951

TCPB
T-complex protein 1 subunit beta

4

20

Small-scale

0.704

High

890997

TCPH
T-complex protein 1 subunit eta

4

20

Small-scale

0.704

High

123892

SPT5H
Transcription elongation factor SPT5

4

13

High-throughput

0.699

High

672395

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

20

High-throughput

0.691

High

890948

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

13

High-throughput

0.691

High

890958

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

1

20

High-throughput

0.691

High

890989

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

3

1

Small-scale

0.675

High

842804

TCPQ
T-complex protein 1 subunit theta

3

20

Small-scale

0.662

High

246559

MCE1
mRNA-capping enzyme

3

4

High-throughput

0.656

High

890952

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

2

19

High-throughput

0.640

High

552375

RFA2
Replication protein A 32 kDa subunit

2

5

Small-scale

0.624

High

890957

TIF1B
Transcription intermediary factor 1-beta

2

9

Small-scale

0.624

High

890991

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

2

20

Small-scale

0.624

High

135416

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

12

High-throughput

0.618

High

890992

SNX27
Sorting nexin-27

1

19

High-throughput

0.618

High

891013

PRP19
Pre-mRNA-processing factor 19

2

4

High-throughput

0.611

High

177248

HDAC3
Histone deacetylase 3

1

9

Small-scale

0.578

High

890954

REL
Proto-oncogene c-Rel

1

8

Small-scale

0.573

High

890967

RBP1
RalA-binding protein 1

2

5

High-throughput

0.571

High

890980

FBX42
F-box only protein 42

2

1

High-throughput

0.558

High

327054

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

9

High-throughput

0.553

High

891009

CALL5
Calmodulin-like protein 5

1

2

High-throughput

0.553

High

891017

TRAF6
TNF receptor-associated factor 6

1

10

Small-scale

0.552

High

131559

STK25
Serine/threonine-protein kinase 25

1

20

High-throughput

0.536

High

175656

TRI18
E3 ubiquitin-protein ligase Midline-1

1

13

High-throughput

0.536

High

203902

HTRA2
Serine protease HTRA2, mitochondrial

1

4

High-throughput

0.536

High

268640

SF3B1
Splicing factor 3B subunit 1

1

16

High-throughput

0.536

High

890945

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

19

High-throughput

0.536

High

890955

FOXD4
Forkhead box protein D4

1

6

High-throughput

0.536

High

890956

LIPA1
Liprin-alpha-1

1

14

High-throughput

0.536

High

890960

CUL3
Cullin-3

1

11

High-throughput

0.536

High

890961

TRI14
Tripartite motif-containing protein 14

1

6

High-throughput

0.536

High

890965

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.536

High

890968

SF3B3
Splicing factor 3B subunit 3

1

1

High-throughput

0.536

High

890969

SF3B4
Splicing factor 3B subunit 4

1

7

High-throughput

0.536

High

890983

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

3

High-throughput

0.536

High

890988

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.536

High

890996

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.536

High

891001

SF3B5
Splicing factor 3B subunit 5

1

1

High-throughput

0.536

High

891002

CDCA4
Cell division cycle-associated protein 4

1

5

High-throughput

0.536

High

891003

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

6

High-throughput

0.536

High

891012

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

13

High-throughput

0.536

High

891015

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

19

High-throughput

0.536

High

891016

SF3B6
Splicing factor 3B subunit 6

1

7

High-throughput

0.536

High

803465

BAG6
Large proline-rich protein BAG6

1

4

High-throughput

0.515

High

254565

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.513

High

278410

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.513

High

451076

SPRC
SPARC

1

0

High-throughput

0.513

High

535824

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

890959

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.513

High

890999

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.513

High

386409

P53
Cellular tumor antigen p53

1

4

Small-scale

0.501

High

401727

JUN
Transcription factor Jun

1

7

Small-scale

0.501

High

890942

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

2

High-throughput

0.501

High

890953

TF65
Transcription factor p65

1

5

Small-scale

0.501

High

890974

TCHL1
Trichohyalin-like protein 1

1

3

High-throughput

0.489

High

890994

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

890995

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

378663

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

158435

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

20

Small-scale

0.479

High

162564

XPO1
Exportin-1

1

7

High-throughput

0.479

High

167506

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

20

Small-scale

0.479

High

175376

PPM1D
Protein phosphatase 1D

1

1

Small-scale

0.479

High

182639

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

227015

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

244189

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

297328

MYO1D
Unconventional myosin-Id

1

11

High-throughput

0.479

High

551650

DESP
Desmoplakin

1

7

High-throughput

0.479

High

587487

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

12

Small-scale

0.479

High

613970

TBG1
Tubulin gamma-1 chain

1

6

Small-scale

0.479

High

650822

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

720107

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

890946

DYLT1
Dynein light chain Tctex-type 1

1

3

High-throughput

0.479

High

890947

SPT4H
Transcription elongation factor SPT4

1

1

High-throughput

0.479

High

890949

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.479

High

890962

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

18

High-throughput

0.479

High

890963

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.479

High

890972

WDR81
WD repeat-containing protein 81

1

5

High-throughput

0.479

High

890976

ATD3B
ATPase family AAA domain-containing protein 3B

1

13

High-throughput

0.479

High

890981

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

890982

TRM1L
TRMT1-like protein

1

1

High-throughput

0.479

High

890985

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

890986

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

890990

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.479

High

891004

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

891005

ADT4
ADP/ATP translocase 4

1

2

High-throughput

0.479

High

891006

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.479

High

891010

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

891014

SRRM2
Serine/arginine repetitive matrix protein 2

1

12

High-throughput

0.479

High

891019

NEMO
NF-kappa-B essential modulator

1

12

Small-scale

0.479

High

120143

TLR4
Toll-like receptor 4

1

0

Small-scale

0.458

High

237043

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.458

High

264193

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.458

High

532455

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

883961

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.458

High

890971

SMN
Survival motor neuron protein

1

0

Small-scale

0.458

High

890998

GCP2
Gamma-tubulin complex component 2

1

0

Small-scale

0.458

High

891000

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.458

High

890984

ZN695
Zinc finger protein 695

1

6

High-throughput

0.445

High

891007

ATD3A
ATPase family AAA domain-containing protein 3A

1

13

High-throughput

0.437

High

483681

CT456
Cancer/testis antigen family 45 member A6

1

4

High-throughput

0.407

High

890943

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.279

Low

890975

GLYL3
Glycine N-acyltransferase-like protein 3

1

0

High-throughput

0.279

Low

68624

TTC34
Tetratricopeptide repeat protein 34

1

0

High-throughput

0.249

Low

890993

UBX10
UBX domain-containing protein 10

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024