HitPredict

Interactor 1: POF2 (O74783)
SCF E3 ubiquitin ligase complex F-box protein pof2 (F-box and leucine-rich repeat protein pof2) (F-box/LRR-repeat protein pof2) (F-box protein pof2)
Gene: POF2

Interactor 2: SKP1 (Q9Y709)
Suppressor of kinetochore protein 1 (P19/Skp1 homolog)
Gene: SKP1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15147268
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	F-box-like~Skp1
Common GO terms	GO:0005737 - cytoplasm GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Sp			1 161
+	Hs
		929099 FBXL7_HUMAN (2-444): 2.21e-67: 225: 20.45		SKP1_HUMAN (1-161): 9e-82: 240: 55.76
+	Sc
		624307 GRR1_YEAST (3-461): 2.72e-71: 246: 28.48		SKP1_YEAST (2-161): 5.56e-66: 201: 50.00
+	At
		1123017 TIR1_ARATH (1-415): 3.29e-50: 181: 18.14		ASK4_ARATH (4-158): 3.73e-80: 235: 44.52
+	Mm
		58200 FXL16_MOUSE (5-383): 1.57e-48: 174: 20.62		SKP1_MOUSE (1-161): 8.42e-82: 240: 55.76
+	At
		1107609 FBX14_ARATH (5-437): 4.59e-53: 189: 17.52		SKP1A_ARATH (3-158): 1.64e-75: 224: 51.28
+	At
		1123022 TIR1_ARATH (1-415): 3.29e-50: 181: 18.14		ASK3_ARATH (4-158): 1.93e-78: 231: 43.23
+	At
		1107590 TIR1_ARATH (1-415): 3.29e-50: 181: 18.14		SKP1A_ARATH (3-158): 1.64e-75: 224: 51.28
+	At
		1123015 TIR1_ARATH (1-415): 3.29e-50: 181: 18.14		SKP1B_ARATH (3-158): 1e-73: 220: 48.49
+	At
		221642 TIR1_ARATH (1-415): 3.29e-50: 181: 18.14		ASK11_ARATH (4-158): 3.3e-74: 220: 50.32
+	At
		1123019 TIR1_ARATH (1-415): 3.29e-50: 181: 18.14		ASK9_ARATH (3-158): 1.3e-72: 216: 42.04
+	Hs
		928985 FXL16_HUMAN (7-383): 4.86e-39: 149: 20.73		SKP1_HUMAN (1-161): 9e-82: 240: 55.76
+	At
		1338929 BRL1_ARATH (31-407): 1.04e-35: 142: 11.80		ASK4_ARATH (4-158): 3.73e-80: 235: 44.52
+	Hs
		928983 FXL14_HUMAN (194-462): 9.73e-35: 135: 18.79		SKP1_HUMAN (1-161): 9e-82: 240: 55.76
+	Ce
		105464 FBXL_CAEEL (174-457): 1.86e-36: 141: 20.63		SKR1_CAEEL (3-160): 1.7e-78: 232: 56.10
+	Mm
		1321913 FXL20_MOUSE (148-463): 5.9e-32: 128: 20.56		SKP1_MOUSE (1-161): 8.42e-82: 240: 55.76
+	Hs
		929033 FXL20_HUMAN (148-463): 3.98e-32: 128: 20.56		SKP1_HUMAN (1-161): 9e-82: 240: 55.76
+	Dm
		285046 Q9W214_DROME (208-443): 3.77e-34: 136: 21.95		O77430_DROME (1-161): 5.17e-78: 230: 56.71
+	At
		1107642 Q9FMW7_ARATH (44-312): 1.83e-30: 123: 17.65		SKP1A_ARATH (3-158): 1.64e-75: 224: 51.28
+	Dm
		284984 Q7K0V7_DROME (64-379): 2.93e-27: 117: 14.77		O77430_DROME (1-161): 5.17e-78: 230: 56.71
+	At
		1323347 Q9FMW7_ARATH (44-312): 1.83e-30: 123: 17.65		SKP1B_ARATH (3-158): 1e-73: 220: 48.49