HitPredict

Interactor 1: BTB1 (O74881)
BTB/POZ domain-containing protein 1
Gene: BTB1

Interactor 2: CUL3 (Q09760)
Cullin-3 (Cul-3)
Gene: CUL3

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	14527422
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1347 Sp			1 785
+	Hs
		1042716 IBTK_HUMAN (11-1268): 0: 659: 20.06		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Mm
		1169620 IBTK_MOUSE (11-1268): 0: 656: 19.74		CUL3_MOUSE (2-785): 0: 801: 35.97
+	Hs
		1041780 BTBD8_HUMAN (619-1225): 2.15e-100: 356: 14.96		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Hs
		1043624 RCC2_HUMAN (296-660): 1.86e-67: 239: 14.29		CUL4B_HUMAN (1-785): 0: 781: 31.26
+	Hs
		1041654 HERC1_HUMAN (34-379): 1.84e-54: 212: 18.49		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Hs
		1042791 HERC5_HUMAN (38-320): 1.28e-47: 188: 18.27		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Hs
		307251 RCBT2_HUMAN (27-334): 6.91e-49: 185: 16.98		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Hs
		1043285 HERC5_HUMAN (38-320): 1.28e-47: 188: 18.27		CUL4A_HUMAN (1-785): 0: 792: 31.89
+	Hs
		1043636 HERC5_HUMAN (38-320): 1.28e-47: 188: 18.27		CUL4B_HUMAN (1-785): 0: 781: 31.26
+	Hs
		578433 RCC1_HUMAN (35-373): 1.21e-36: 146: 18.41		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Hs
		1042070 RCBT1_HUMAN (10-278): 5.62e-34: 140: 15.27		CUL3_HUMAN (2-785): 0: 803: 35.97
+	Hs
		1041254 HERC5_HUMAN (38-320): 1.28e-47: 188: 18.27		CUL1_HUMAN (10-785): 0: 721: 26.12
+	Hs
		1041097 RCBT1_HUMAN (10-278): 5.62e-34: 140: 15.27		CUL1_HUMAN (10-785): 0: 721: 26.12
+	Hs
		1041493 HERC5_HUMAN (38-320): 1.28e-47: 188: 18.27		CUL2_HUMAN (13-785): 0: 671: 23.51
+	Hs
		1041402 RCBT1_HUMAN (10-278): 5.62e-34: 140: 15.27		CUL2_HUMAN (13-785): 0: 671: 23.51
+	Hs
		1274076 HERC5_HUMAN (38-320): 1.28e-47: 188: 18.27		CUL5_HUMAN (19-785): 0: 592: 21.19
+	Hs
		1242534 RCBT1_HUMAN (10-278): 5.62e-34: 140: 15.27		CUL5_HUMAN (19-785): 0: 592: 21.19