Interactor 1: DEPD5 (O75140)
GATOR1 complex protein DEPDC5 (DEP domain-containing protein 5)
Gene: DEPDC5

Interactor 2: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.886

The method score is based on:

Property Details
Experiments 28199306, 28199315, 23723238, 35831510
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEP~WD40
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0034198 - cellular response to amino acid starvation
GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1603
Hs

1 790
+ Hs
+ Hs
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024