HitPredict

Interactor 1: DEPD5 (O75140)
GATOR1 complex protein DEPDC5 (DEP domain-containing protein 5)
Gene: DEPDC5

Interactor 2: RRAGC (Q9HB90)
Ras-related GTP-binding protein C (Rag C) (RagC) (EC 3.6.5.-) (GTPase-interacting protein 2) (TIB929)
Gene: RRAGC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	23723238, 28199315, 25366275
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0034198 - cellular response to amino acid starvation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1603 Hs			1 399
+	Hs
		255000 DEPD5_HUMAN (1-1603): 0: 2753: 100.00		RRAGD_HUMAN (25-396): 0: 527: 80.91
+	Hs
		254988 DEPD5_HUMAN (1-1603): 0: 2753: 100.00		RRAGA_HUMAN (53-284): 3.26e-105: 314: 26.27
+	Hs
		254984 DEPD5_HUMAN (1-1603): 0: 2753: 100.00		RRAGB_HUMAN (43-284): 9.91e-104: 313: 24.09
+	Sc
		812608 IML1_YEAST (1204-1514): 4.03e-74: 275: 21.86		RAGAB_YEAST (57-353): 2.35e-89: 274: 20.98