Interactor 1: ICOSL (O75144)
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
Gene: ICOSLG
Interactor 2: ICOSL (O75144)
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
Gene: ICOSLG
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.57 | 1.00 | 0.761 |
The method score is based on:
Property | Details |
---|---|
Experiments | 16951355 |
Identification Methods | molecular sieving, comigration in non denaturing gel electrophoresis, cross-linking study, fluorescent resonance energy transfer |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | V-set~V-set |
Common GO terms | GO:0001817 - regulation of cytokine production GO:0002250 - adaptive immune response GO:0005102 - signaling receptor binding GO:0005886 - plasma membrane GO:0006952 - defense response and 10 others more... |
Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024