Interactor 1: ICOSL (O75144)
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
Gene: ICOSLG

Interactor 2: ICOSL (O75144)
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
Gene: ICOSLG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.761

The method score is based on:

Property Details
Experiments 16951355
Identification Methods molecular sieving, comigration in non denaturing gel electrophoresis, cross-linking study, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains V-set~V-set
Common GO terms GO:0001817 - regulation of cytokine production
GO:0002250 - adaptive immune response
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0006952 - defense response
and 10 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 302
Hs

1 302
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024