HitPredict

Interactor 1: LIPA3 (O75145)
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)
Gene: PPFIA3

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0050808 - synapse organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 758
+	Hs
		259636 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496439 MYH10_HUMAN (430-955): 3.85e-14: 79.8: 7.18		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497769 MYH2_HUMAN (3-402): 2.33e-12: 74: 12.56		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496438 MYH9_HUMAN (472-901): 3.35e-12: 73.6: 9.07		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582036 MYH10_RAT (430-955): 2.7e-14: 80.2: 7.56		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94262 MYH10_RAT (430-955): 2.7e-14: 80.2: 7.56		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Dm
		1370297 Q9VU88_DROME (582-1139): 6.49e-63: 230: 18.46		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96