HitPredict

Interactor 1: LIPA3 (O75145)
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)
Gene: PPFIA3

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	27880917, 28330616, 18782753, 35271311
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 309
+	Hs
		255240 LIPA3_HUMAN (1-1194): 6.31e-178: 557: 100.00		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		930827 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915178 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		259641 LIPA2_HUMAN (1-1194): 1.21e-124: 416: 54.80		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		890956 LIPA1_HUMAN (1-1194): 6.96e-129: 426: 57.54		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Dm
		114419 M9PCD4_DROME (1-1118): 3.24e-75: 274: 36.17		PP2A_DROME (1-309): 0: 524: 93.85
+	Hs
		930910 LIPB1_HUMAN (288-1139): 1.86e-68: 251: 17.92		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		725131 MYH10_HUMAN (430-955): 3.85e-14: 79.8: 7.18		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		724764 MYH9_HUMAN (472-901): 3.35e-12: 73.6: 9.07		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		724689 MYH9_HUMAN (472-901): 3.35e-12: 73.6: 9.07		PP1G_HUMAN (7-306): 0: 505: 45.96
+	Hs
		724746 MYH9_HUMAN (472-901): 3.35e-12: 73.6: 9.07		PP1A_HUMAN (5-296): 0: 504: 46.51