HitPredict

Interactor 1: TOM1 (O60784)
Target of Myb1 membrane trafficking protein (Target of Myb protein 1)
Gene: TOM1

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	31527615, 34591612, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction and 1 others more... GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 595
+	Hs
		396379 TM1L2_HUMAN (1-492): 2.33e-147: 432: 61.45		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		256491 TOM1_HUMAN (1-492): 5.21e-178: 510: 100.00		ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88
+	Hs
		1256895 TM1L2_HUMAN (1-492): 2.33e-147: 432: 61.45		ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88
+	Hs
		1366933 STAM1_HUMAN (1-477): 6.11e-92: 291: 19.27		ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88
+	Hs
		169678 HGS_HUMAN (10-465): 5.14e-76: 255: 17.90		ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88
+	Hs
		256438 TOM1_HUMAN (1-492): 5.21e-178: 510: 100.00		ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16
+	Hs
		169496 HGS_HUMAN (10-465): 5.14e-76: 255: 17.90		ERR3_HUMAN (91-547): 2.28e-116: 355: 33.77
+	Hs
		520151 TM1L2_HUMAN (1-492): 2.33e-147: 432: 61.45		ANDR_HUMAN (172-455): 8.99e-37: 148: 30.16