Protein: ERR3
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)

Gene: ERR3, ESRRG
Organism: Homo sapiens
Interactions: 80
UniProt ID: P62508

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003707 - nuclear steroid receptor activity
GO:0004879 - nuclear receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

543569

ERR1
Steroid hormone receptor ERR1

7

19

Small-scale

0.959

High

976885

ERR3
Estrogen-related receptor gamma

6

19

Small-scale

0.944

High

908326

NR0B1
Nuclear receptor subfamily 0 group B member 1

5

20

High-throughput

0.927

High

976897

NR0B2
Nuclear receptor subfamily 0 group B member 2

5

19

Small-scale

0.925

High

343246

ERR2
Steroid hormone receptor ERR2

3

20

High-throughput

0.858

High

976898

NCOA1
Nuclear receptor coactivator 1

2

20

Small-scale

0.767

High

976929

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

6

20

Small-scale

0.732

High

873935

NRIP1
Nuclear receptor-interacting protein 1

6

15

Small-scale

0.725

High

976927

PNRC2
Proline-rich nuclear receptor coactivator 2

4

15

Small-scale

0.688

High

968868

PRS8
26S proteasome regulatory subunit 8

3

20

High-throughput

0.654

High

976907

PRGC2
Peroxisome proliferator-activated receptor gamma coactivator 1-beta

3

20

High-throughput

0.647

High

976889

DEUP1
Deuterosome assembly protein 1

3

20

High-throughput

0.616

High

976915

PROX1
Prospero homeobox protein 1

2

2

High-throughput

0.614

High

659432

CRCM
Colorectal mutant cancer protein

2

9

High-throughput

0.606

High

685149

PAX6
Paired box protein Pax-6

2

11

High-throughput

0.606

High

877767

TNNI2
Troponin I, fast skeletal muscle

2

3

High-throughput

0.606

High

976888

REL
Proto-oncogene c-Rel

2

20

High-throughput

0.606

High

976892

ATM
Serine-protein kinase ATM

2

13

High-throughput

0.606

High

976893

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

10

High-throughput

0.606

High

976895

EXOS7
Exosome complex component RRP42

2

8

High-throughput

0.606

High

976902

VAX1
Ventral anterior homeobox 1

2

10

High-throughput

0.606

High

976905

ZN438
Zinc finger protein 438

2

16

High-throughput

0.606

High

976913

SNIP1
Smad nuclear-interacting protein 1

2

4

High-throughput

0.606

High

976919

TREF1
Transcriptional-regulating factor 1

2

20

High-throughput

0.606

High

976903

MRM1
rRNA methyltransferase 1, mitochondrial

3

6

High-throughput

0.591

High

352757

F107A
Actin-associated protein FAM107A

2

0

High-throughput

0.580

High

377053

COLI
Pro-opiomelanocortin

2

0

High-throughput

0.580

High

976909

RBIS
Ribosomal biogenesis factor

2

0

High-throughput

0.580

High

893807

MEOX2
Homeobox protein MOX-2

1

14

High-throughput

0.573

High

976899

HIF1A
Hypoxia-inducible factor 1-alpha

1

20

Small-scale

0.561

High

976931

DNM3L
DNA

1

6

Small-scale

0.561

High

619240

TNNI1
Troponin I, slow skeletal muscle

2

3

High-throughput

0.553

High

976894

FASTK
Fas-activated serine/threonine kinase

2

3

High-throughput

0.553

High

976900

EFHC2
EF-hand domain-containing family member C2

2

1

High-throughput

0.553

High

976908

FAM9A
Protein FAM9A

2

1

High-throughput

0.553

High

976912

ADCY4
Adenylate cyclase type 4

2

1

High-throughput

0.553

High

976920

UBL7
Ubiquitin-like protein 7

2

1

High-throughput

0.553

High

976921

SRPK1
SRSF protein kinase 1

1

16

High-throughput

0.550

High

976901

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.536

High

193098

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

10

High-throughput

0.536

High

262051

NBN
Nibrin

1

4

High-throughput

0.536

High

413552

P53
Cellular tumor antigen p53

1

7

High-throughput

0.536

High

892833

MRE11
Double-strand break repair protein MRE11

1

2

High-throughput

0.536

High

976916

RAD50
DNA repair protein RAD50

1

20

High-throughput

0.536

High

976890

NU160
Nuclear pore complex protein Nup160

1

1

High-throughput

0.523

High

976923

KIFC3
Kinesin-like protein KIFC3

1

4

High-throughput

0.523

High

279329

TULP3
Tubby-related protein 3

1

0

High-throughput

0.518

High

107797

SUMO5
Small ubiquitin-related modifier 5

1

10

High-throughput

0.515

High

169496

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

15

Small-scale

0.501

High

421869

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

464895

SP1
Transcription factor Sp1

1

20

Small-scale

0.501

High

976887

TLE1
Transducin-like enhancer protein 1

1

20

Small-scale

0.501

High

976926

SRA1
Steroid receptor RNA activator 1

1

3

Small-scale

0.501

High

976932

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

9

High-throughput

0.489

High

751312

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

2

High-throughput

0.481

High

976891

PNRC1
Proline-rich nuclear receptor coactivator 1

1

15

High-throughput

0.481

High

241311

PRKN
E3 ubiquitin-protein ligase parkin

1

7

Small-scale

0.479

High

325775

UBR5
E3 ubiquitin-protein ligase UBR5

1

18

Small-scale

0.479

High

851494

GATA4
Transcription factor GATA-4

1

9

High-throughput

0.479

High

939173

SUMO3
Small ubiquitin-related modifier 3

1

10

Small-scale

0.479

High

976928

ZHANG
CREB/ATF bZIP transcription factor

1

2

Small-scale

0.479

High

976930

CGBP1
CGG triplet repeat-binding protein 1

1

1

High-throughput

0.445

High

324289

ARHGF
Rho guanine nucleotide exchange factor 15

1

16

High-throughput

0.439

High

345625

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.437

High

976917

ARK2N
Protein ARK2N

1

0

High-throughput

0.426

High

553162

KCRB
Creatine kinase B-type

1

3

High-throughput

0.407

High

976918

PCMD1
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1

1

3

High-throughput

0.407

High

976925

TRPM3
Transient receptor potential cation channel subfamily M member 3

1

4

High-throughput

0.407

High

49306

SHOT1
Shootin-1

3

0

High-throughput

0.352

High

976904

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.316

High

976906

BPHL
Serine hydrolase BPHL

2

0

High-throughput

0.316

High

976924

EVG1
UPF0193 protein EVG1

2

0

High-throughput

0.316

High

976911

ACOT4
Peroxisomal succinyl-coenzyme A thioesterase

1

0

High-throughput

0.279

Low

976922

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.279

Low

976896

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.251

Low

976910

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

976914

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.249

Low

389810

TTHY
Transthyretin

1

0

High-throughput

0.232

Low

976886

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025