HitPredict

Interactor 1: PP6R2 (O75170)
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
Gene: PPP6R2

Interactor 2: MOB1B (Q7L9L4)
MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A)
Gene: MOB1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	37536630, 24255178
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 966 Hs			1 216
+	Hs
		257223 PP6R2_HUMAN (1-966): 0: 893: 100.00		MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83
+	Hs
		257191 PP6R2_HUMAN (1-966): 0: 893: 100.00		MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80
+	Hs
		1125998 PP6R3_HUMAN (1-914): 0: 746: 46.31		MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00
+	Hs
		1126044 PP6R3_HUMAN (1-914): 0: 746: 46.31		MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83
+	Hs
		1185505 PP6R1_HUMAN (1-898): 0: 640: 39.94		MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00
+	Hs
		1333713 PP6R1_HUMAN (1-898): 0: 640: 39.94		MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83
+	Hs
		1285991 PP6R1_HUMAN (1-898): 0: 640: 39.94		MOB3A_HUMAN (5-212): 3.88e-106: 306: 53.11
+	Hs
		1174334 PP6R1_HUMAN (1-898): 0: 640: 39.94		MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80
+	Hs
		1174251 HUWE1_HUMAN (487-954): 7.07e-26: 118: 13.22		MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80