Interactor 1: LRP5 (O75197)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5

Interactor 2: NDP (Q00604)
Norrin (Norrie disease protein) (X-linked exudative vitreoretinopathy 2 protein)
Gene: NDP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 19837033
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0035426 - extracellular matrix-cell signaling
GO:0045893 - positive regulation of DNA-templated transcription
GO:0060070 - canonical Wnt signaling pathway
GO:0060856 - establishment of blood-brain barrier
GO:0061304 - retinal blood vessel morphogenesis
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1615
Hs

1 133
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024