Interactor 1: LRP5 (O75197)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5
Interactor 2: FZD8 (Q9H461)
Frizzled-8 (Fz-8) (hFz8)
Gene: FZD8
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 0.60 | 0.501 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11448771 |
Identification Methods | pull down |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005886 - plasma membrane GO:0017147 - Wnt-protein binding GO:0042813 - Wnt receptor activity GO:0060070 - canonical Wnt signaling pathway GO:1990851 - Wnt-Frizzled-LRP5/6 complex |
Homologous interactions | 4 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024