Protein: TRI13
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)

Gene: TRI13, TRIM13
Organism: Homo sapiens
Interactions: 155
UniProt ID: O60858

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

258214

TRI13
E3 ubiquitin-protein ligase TRIM13

3

18

Small-scale

0.835

High

258270

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.778

High

144152

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

168478

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

20

Small-scale

0.647

High

258251

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

20

Small-scale

0.647

High

258256

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

Small-scale

0.647

High

258263

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

258264

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

20

Small-scale

0.647

High

258265

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.647

High

258268

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

Small-scale

0.647

High

258271

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

20

Small-scale

0.647

High

258281

SQSTM
Sequestosome-1

3

11

Small-scale

0.640

High

258345

ELOV2
Very long chain fatty acid elongase 2

2

1

High-throughput

0.628

High

258357

COMDA
COMM domain-containing protein 10

2

3

High-throughput

0.628

High

258279

CKAP4
Cytoskeleton-associated protein 4

2

19

High-throughput

0.611

High

258311

NPL4
Nuclear protein localization protein 4 homolog

2

0

High-throughput

0.602

High

258235

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

2

15

Small-scale

0.584

High

258260

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

258352

ALK
ALK tyrosine kinase receptor

2

8

High-throughput

0.584

High

258215

LRRN2
Leucine-rich repeat neuronal protein 2

2

3

High-throughput

0.574

High

258247

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

2

High-throughput

0.574

High

258240

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

Small-scale

0.561

High

258273

CCNA1
Cyclin-A1

1

1

Small-scale

0.561

High

258276

MDM2
E3 ubiquitin-protein ligase Mdm2

1

5

Small-scale

0.561

High

258332

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

258340

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.513

High

258348

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.513

High

258308

TM35B
Transmembrane protein 35B

1

2

High-throughput

0.489

High

48456

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.479

High

173789

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.479

High

258220

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

258221

RASK
GTPase KRas

1

8

High-throughput

0.479

High

258222

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

258223

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

258224

INSR
Insulin receptor

1

9

High-throughput

0.479

High

258226

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

258229

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

4

Small-scale

0.479

High

258230

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

258231

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.479

High

258232

RAB3B
Ras-related protein Rab-3B

1

4

High-throughput

0.479

High

258234

RAB5A
Ras-related protein Rab-5A

1

9

High-throughput

0.479

High

258236

CALX
Calnexin

1

2

High-throughput

0.479

High

258238

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

7

High-throughput

0.479

High

258241

VGFR3
Vascular endothelial growth factor receptor 3

1

3

High-throughput

0.479

High

258242

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.479

High

258252

EMD
Emerin

1

1

High-throughput

0.479

High

258254

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.479

High

258255

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

258258

BI1
Bax inhibitor 1

1

3

High-throughput

0.479

High

258259

TERA
Transitional endoplasmic reticulum ATPase

1

4

Small-scale

0.479

High

258261

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

258262

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.479

High

258266

CSN2
COP9 signalosome complex subunit 2

1

6

High-throughput

0.479

High

258267

RHOA
Transforming protein RhoA

1

6

High-throughput

0.479

High

258272

CXAR
Coxsackievirus and adenovirus receptor

1

9

High-throughput

0.479

High

258274

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

258283

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

Small-scale

0.479

High

258284

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

6

High-throughput

0.479

High

258286

BECN1
Beclin-1

1

4

Small-scale

0.479

High

258289

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.479

High

258294

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

258297

SYNE3
Nesprin-3

1

10

High-throughput

0.479

High

258299

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

4

High-throughput

0.479

High

258307

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

258309

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

Small-scale

0.479

High

258312

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.479

High

258315

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.479

High

258318

LRC59
Leucine-rich repeat-containing protein 59

1

4

High-throughput

0.479

High

258319

TECT2
Tectonic-2

1

2

High-throughput

0.479

High

258321

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

258322

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

4

High-throughput

0.479

High

258328

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.479

High

258330

DERL1
Derlin-1

1

1

High-throughput

0.479

High

258333

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.479

High

258339

AT131
Endoplasmic reticulum transmembrane helix translocase

1

6

High-throughput

0.479

High

258346

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

258351

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

258353

VPS4A
Vacuolar protein sorting-associated protein 4A

1

11

High-throughput

0.479

High

258356

TRAF6
TNF receptor-associated factor 6

1

18

Small-scale

0.479

High

258358

NEMO
NF-kappa-B essential modulator

1

20

Small-scale

0.479

High

258293

Q53SE7
Germ cell-less homolog 1

1

15

High-throughput

0.470

High

258216

MTX2
Metaxin-2

1

0

High-throughput

0.458

High

258218

CNEP1
CTD nuclear envelope phosphatase 1

1

0

High-throughput

0.458

High

258228

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

258239

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.458

High

258243

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

Small-scale

0.458

High

258245

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

258246

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

258250

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

258282

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

258300

LBN
Limbin

1

0

High-throughput

0.458

High

258323

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

258326

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

258327

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

258329

TMM43
Transmembrane protein 43

1

0

High-throughput

0.458

High

258331

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

258334

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

258341

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

258344

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

258349

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

258296

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.445

High

258320

GMCL1
Germ cell-less protein-like 1

1

15

High-throughput

0.439

High

258338

ROBO2
Roundabout homolog 2

1

2

High-throughput

0.439

High

188741

TMPS2
Transmembrane protease serine 2

1

5

High-throughput

0.437

High

189340

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

217596

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

258225

IGF1R
Insulin-like growth factor 1 receptor

1

10

High-throughput

0.437

High

258227

FGFR1
Fibroblast growth factor receptor 1

1

6

High-throughput

0.437

High

258233

RAB4A
Ras-related protein Rab-4A

1

5

High-throughput

0.437

High

258237

EPHA8
Ephrin type-A receptor 8

1

13

High-throughput

0.437

High

258244

CEAM6
Cell adhesion molecule CEACAM6

1

4

High-throughput

0.437

High

258248

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

2

High-throughput

0.437

High

258253

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.437

High

258269

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.437

High

258277

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

9

High-throughput

0.437

High

258280

STX4
Syntaxin-4

1

2

High-throughput

0.437

High

258288

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.437

High

258290

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

4

High-throughput

0.437

High

258295

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

258298

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.437

High

258303

MIRO2
Mitochondrial Rho GTPase 2

1

13

High-throughput

0.437

High

258304

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

258306

DJC22
DnaJ homolog subfamily C member 22

1

3

High-throughput

0.437

High

258350

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.437

High

258355

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.437

High

258291

S35G1
Solute carrier family 35 member G1

1

0

High-throughput

0.426

High

258310

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

258219

MOT3
Monocarboxylate transporter 3

1

4

High-throughput

0.407

High

258249

SL9A3
Sodium/hydrogen exchanger 3

1

2

High-throughput

0.407

High

258287

SL9A5
Sodium/hydrogen exchanger 5

1

2

High-throughput

0.407

High

258292

CTL4
Choline transporter-like protein 4

1

1

High-throughput

0.407

High

258314

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.407

High

258325

SL9A7
Sodium/hydrogen exchanger 7

1

2

High-throughput

0.407

High

60695

F234B
Protein FAM234B

2

0

High-throughput

0.328

High

191949

TEX28
Testis-specific protein TEX28

2

0

High-throughput

0.328

High

258285

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

0

High-throughput

0.279

Low

258305

TM130
Transmembrane protein 130

1

0

High-throughput

0.279

Low

258313

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

258335

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

258336

KCNF1
Voltage-gated potassium channel regulatory subunit KCNF1

1

0

High-throughput

0.279

Low

258354

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

1

0

High-throughput

0.279

Low

258278

KIME
Mevalonate kinase

1

0

High-throughput

0.269

Low

258257

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.251

Low

258217

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

258275

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

258301

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

258302

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

258316

AP3S1
AP-3 complex subunit sigma-1

1

0

High-throughput

0.249

Low

258317

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

258337

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

258342

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

258343

ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

1

0

High-throughput

0.249

Low

258347

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

258324

S26A8
Testis anion transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025