HitPredict

Interactor 1: SEM7A (O75326)
Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108)
Gene: SEMA7A

Interactor 2: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 666 Hs			1 377
+	Hs
		557792 SEM6A_HUMAN (24-570): 8.82e-163: 496: 23.19		NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00
+	Hs
		259518 SEM7A_HUMAN (1-666): 0: 698: 100.00		FYN_HUMAN (7-173): 7.47e-21: 96: 15.39
+	Hs
		259523 SEM7A_HUMAN (1-666): 0: 698: 100.00		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		209166 SEM6A_HUMAN (24-570): 8.82e-163: 496: 23.19		NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24
+	Hs
		299000 SEM6A_HUMAN (24-570): 8.82e-163: 496: 23.19		SRBS2_HUMAN (64-287): 1.79e-23: 104: 18.26
+	Hs
		1329264 SEM6A_HUMAN (24-570): 8.82e-163: 496: 23.19		ITSN2_HUMAN (7-85): 2.68e-12: 70.6: 24.05