HitPredict

Interactor 1: HMMR (O75330)
Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)
Gene: HMMR

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	22110403, 25184681, 26831064
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 1863
+	Hs
		724691 MYH9_HUMAN (97-724): 2e-28: 124: 14.02		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		725099 MYH10_HUMAN (306-724): 5.15e-16: 84.6: 14.62		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		148473 CTRO_HUMAN (215-683): 6.31e-13: 74.6: 12.37		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		551628 DESP_HUMAN (46-680): 1.2e-09: 64.2: 13.19		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Xl
		1145422 Q643Y9_XENLA (24-488): 1.09e-12: 73.9: 12.42		Q90X96_XENLA (1-846): 8.6e-74: 275: 22.02
+	Hs
		522639 MYH7_HUMAN (2-344): 2.22e-11: 69.6: 11.59		TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54
+	Hs
		528393 MYH6_HUMAN (2-355): 3.97e-11: 68.8: 11.80		TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54
+	Hs
		149258 CTRO_HUMAN (215-683): 6.31e-13: 74.6: 12.37		TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52
+	Hs
		725005 MYH9_HUMAN (97-724): 2e-28: 124: 14.02		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Hs
		725238 MYH10_HUMAN (306-724): 5.15e-16: 84.6: 14.62		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30
+	Mm
		1093546 MYH9_MOUSE (355-724): 2.35e-13: 76.2: 13.87		TRI72_MOUSE (18-91): 9.41e-12: 71.5: 30.26