Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: PEF1 (Q9UBV8)
Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1)
Gene: PEF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 27716508, 32296183, 11278427, 33961781, 35120648, 25416956, 21516116, 35271311, 21988832, unassigned1304, 16189514
Identification Methods affinity chromatography technology, pull down, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_6~EF-hand_7, EF-hand_7~EF-hand_7
Common GO terms GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0014029 - neural crest formation
and 10 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 191
Hs

1 284
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Last updated: 15 Jul 2024