HitPredict

Interactor 1: VATG1 (O75348)
V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)
Gene: ATP6V1G1

Interactor 2: VATE1 (P36543)
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)
Gene: ATP6V1E1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 16169070, 35271311, 35235311, 33961781
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_G~vATP-synt_E
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0016241 - regulation of macroautophagy
GO:0016324 - apical plasma membrane
and 5 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 118
Hs

1 226
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs
+ Zm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024